Drug profile

The FDA adverse-event record for Herbal Supplement

48 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Herbal Supplement. See the species affected, top reactions, and outcomes below.

48
adverse-event reports
16.7%
death-coded share
Dog
most-reported species
11
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
48
Total Reports
8
Deaths Reported
16.7%
Death Rate

Active Ingredients

Herbal Supplement

Administration Routes

UnknownOral

Species Affected

Dog 42
Cat 6

Most Affected Breeds

Retriever - Labrador 12
Domestic Shorthair 5
Shih Tzu 2
Collie - Border 2
Beagle 2
Dachshund - Miniature 2
Retriever - Golden 2
Dog (unknown) 1
Boxer (German Boxer) 1
Corgi (unspecified) 1

Most Reported Reactions

Vomiting 11
Death by euthanasia 5
Ataxia 5
Weight loss 5
Diarrhoea 5
Anorexia 4
Elevated blood urea nitrogen (BUN) 4
Lack of efficacy - NOS 4
Not eating 4
Loose stool 4
Panting 4
Decreased appetite 4

Outcome Breakdown

Ongoing
20 (41.7%)
Outcome Unknown
11 (22.9%)
Recovered/Normal
9 (18.8%)
Euthanized
5 (10.4%)
Died
3 (6.3%)

Herbal Supplement Adverse Event Insights

48 reports name Herbal Supplement; 8 recorded a death outcome (16.7% of reported events, not a population-level mortality rate). Active ingredient: Herbal Supplement. Administration routes: Unknown, Oral.

By species: Dog (42 reports), Cat (6 reports). By breed: Retriever - Labrador (12), Domestic Shorthair (5), Shih Tzu (2).

Leading clinical signs: Vomiting (11), Death by euthanasia (5), Ataxia (5), Weight loss (5). Outcome, 48 coded reports: Ongoing leads at 41.7%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.