Heartworm Prevention (Unknown)
969 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
969
Total Reports
27
Deaths Reported
280.0%
Death Rate
Active Ingredients
Heartworm Prevention (Unknown)
Administration Routes
UnknownOralTopical
Species Affected
Dog 960
Cat 8
Unknown 1
Most Affected Breeds
Retriever - Labrador 96
Chihuahua 55
Crossbred Canine/dog 49
Terrier - Yorkshire 45
Shih Tzu 44
Shepherd Dog - German 40
Retriever - Golden 32
Pit Bull 32
Maltese 29
Boxer (German Boxer) 22
Most Reported Reactions
Emesis 232
Lack of efficacy (ectoparasite) - flea 160
Vomiting 141
Lack of efficacy (endoparasite) - heartworm 133
Lethargy (see also Central nervous system depression in 'Neurological') 104
Lack of efficacy - NOS 53
Diarrhoea 40
Other abnormal test result NOS 33
Behavioural disorder NOS 32
Decreased appetite 26
Seizure NOS 26
Lack of efficacy (flea) 22
Outcome Breakdown
Outcome Unknown
411 (42.5%)
Recovered/Normal
400 (41.3%)
Ongoing
73 (7.5%)
Recovered with Sequela
57 (5.9%)
Died
22 (2.3%)
Euthanized
5 (0.5%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.