Heartgard Plus
138 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
138
Total Reports
3
Deaths Reported
220.0%
Death Rate
Active Ingredients
Heartgard Plus
Administration Routes
OralUnknown
Species Affected
Dog 138
Most Affected Breeds
Retriever - Labrador 16
Crossbred Canine/dog 11
Chihuahua 10
Terrier - Bull - American Pit 8
Retriever - Golden 7
Shepherd Dog - German 6
Beagle 5
Terrier (unspecified) 4
Shepherd Dog - Australian 3
Shepherd Dog - Belgian Malinois 3
Most Reported Reactions
Lack of efficacy (endoparasite) - heartworm 83
Seizure NOS 8
Polyuria 7
Urinary incontinence 6
Lethargy (see also Central nervous system depression in Neurological) 5
Decreased appetite 4
Vomiting 4
Twitching 4
Emesis (multiple) 4
Diarrhoea 4
Urinary tract infection 4
Ataxia 3
Outcome Breakdown
Ongoing
104 (75.4%)
Outcome Unknown
19 (13.8%)
Recovered/Normal
12 (8.7%)
Euthanized
2 (1.4%)
Died
1 (0.7%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.