Grapiprant

7,974 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

7,974

Total Reports

697

Deaths Reported

870.0%

Death Rate

Active Ingredients

Grapiprant

Administration Routes

OralUnknownOphthalmicTopicalSubcutaneousRectalIntramuscularCutaneousOtherParenteral

Species Affected

Dog 7,308

Unknown 638

Cat 15

Human 13

Most Affected Breeds

Retriever - Labrador 1,239

Dog (unknown) 747

Unknown 665

Retriever - Golden 373

Shepherd Dog - German 356

Crossbred Canine/dog 310

Pit Bull 184

Shepherd Dog - Australian 180

Collie - Border 169

Chihuahua 160

Most Reported Reactions

Vomiting 1,397

Diarrhoea 1,225

Lack of efficacy - NOS 971

Lethargy (see also Central nervous system depression in 'Neurological') 678

Elevated alanine aminotransferase (ALT) 499

Not eating 450

Death by euthanasia 447

Decreased appetite 418

Bloody diarrhoea 384

Tablets, Abnormal 374

Weight loss 342

Elevated blood urea nitrogen (BUN) 328

Outcome Breakdown

Outcome Unknown

2,517 (34.3%)

Ongoing

2,457 (33.5%)

Recovered/Normal

1,630 (22.2%)

Euthanized

447 (6.1%)

Died

252 (3.4%)

Recovered with Sequela

40 (0.5%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.