Drug profile

The FDA adverse-event record for Gnrh

19 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Gnrh. See the species affected, top reactions, and outcomes below.

19
adverse-event reports
5.3%
death-coded share
Cattle
most-reported species
12
Lack of efficacy - NOS - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
19
Total Reports
1
Deaths Reported
5.3%
Death Rate

Active Ingredients

Gnrh

Administration Routes

UnknownIntramuscular

Species Affected

Cattle 19

Most Affected Breeds

Mixed (Cattle) 6
Aberdeen Angus 4
Cattle (other) 3
Cattle (unspecified) 2
Limousin 1
Simmental 1
Hereford cattle 1
Belted Galloway 1

Most Reported Reactions

Lack of efficacy - NOS 12
INEFFECTIVE, ESTRUS SYNCHRONIZ 6
Rectal prolapse 2
Infertility NOS 1
Unexplained death 1
Injection site gaseous gangrene 1
Injection site oedema 1
PR-LUNG(S), LESION(S) 1
Cutaneous emphysema 1
Application site abscess 1
Lateral recumbency 1
Collapse NOS (see also 'Cardio-vascular' and 'Neurological disorders') 1

Outcome Breakdown

Outcome Unknown
15 (78.9%)
Recovered/Normal
3 (15.8%)
Died
1 (5.3%)

Gnrh Adverse Event Insights

19 reports name Gnrh; 1 recorded a death outcome (5.3% of reported events, not a population-level mortality rate). Active ingredient: Gnrh. Administration routes: Unknown, Intramuscular.

By species: Cattle (19 reports). By breed: Mixed (Cattle) (6), Aberdeen Angus (4), Cattle (other) (3).

Leading clinical signs: Lack of efficacy - NOS (12), INEFFECTIVE, ESTRUS SYNCHRONIZ (6), Rectal prolapse (2), Infertility NOS (1). Outcome, 19 coded reports: Outcome Unknown leads at 78.9%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.