Glycosaminoglycan Polysulfate
803 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
803
Total Reports
102
Deaths Reported
1270.0%
Death Rate
Active Ingredients
Glycosaminoglycan Polysulfate
Administration Routes
IntramuscularSubcutaneousUnknownOphthalmicIntra-ArticularOralOther
Species Affected
Dog 665
Cat 66
Unknown 45
Horse 20
Human 6
Other 1
Most Affected Breeds
Retriever - Labrador 129
Crossbred Canine/dog 61
Unknown 53
Shepherd Dog - German 42
Retriever - Golden 39
Domestic (unspecified) 28
Boxer (German Boxer) 27
Dog (unknown) 24
Domestic Shorthair 21
Rottweiler 19
Most Reported Reactions
Vomiting 193
Anorexia 126
Diarrhoea 111
Depression 105
Other abnormal test result NOS 87
Death by euthanasia 68
Lethargy (see also Central nervous system depression in 'Neurological') 60
Elevated serum alkaline phosphatase (SAP) 52
Elevated alanine aminotransferase (ALT) 50
Weight loss 39
Injection site pain 37
Elevated blood urea nitrogen (BUN) 37
Outcome Breakdown
Recovered/Normal
121 (33.9%)
Ongoing
73 (20.4%)
Died
62 (17.4%)
Outcome Unknown
49 (13.7%)
Euthanized
40 (11.2%)
Recovered with Sequela
12 (3.4%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.