Drug profile

The FDA adverse-event record for Glucosamine + Chondroitin + Msm + Hyaluronic Acid

16 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Glucosamine + Chondroitin + Msm + Hyaluronic Acid. See the species affected, top reactions, and outcomes below.

16
adverse-event reports
0.0%
death-coded share
Dog
most-reported species
5
Emesis - top reaction
Verify with FDA CVM →
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
16
Total Reports
0
Deaths Reported
0.0%
Death Rate

Active Ingredients

Glucosamine + Chondroitin + Msm + Hyaluronic Acid

Administration Routes

OralUnknown

Species Affected

Dog 15
Cat 1

Most Affected Breeds

Retriever - Labrador 3
Retriever (unspecified) 2
Terrier - Yorkshire 2
Pit Bull 2
Terrier (unspecified) 1
Spitz - Finnish 1
Chihuahua 1
Terrier - Boston 1
Beagle 1
Bulldog - French 1

Most Reported Reactions

Emesis 5
Vomiting 3
Weight gain 2
Behavioural disorder NOS 1
Sleepiness - neurological disorder 1
Decreased appetite 1
Lethargy (see also Central nervous system depression in 'Neurological') 1
Depression 1
Not eating 1
Other abnormal test result NOS 1
Urine abnormalities NOS 1
Musculoskeletal disorder NOS 1

Outcome Breakdown

Outcome Unknown
7 (43.8%)
Recovered/Normal
6 (37.5%)
Ongoing
3 (18.8%)

Glucosamine + Chondroitin + Msm + Hyaluronic Acid Adverse Event Insights

16 reports name Glucosamine + Chondroitin + Msm + Hyaluronic Acid; 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). Active ingredient: Glucosamine + Chondroitin + Msm + Hyaluronic Acid. Administration routes: Oral, Unknown.

By species: Dog (15 reports), Cat (1 reports). By breed: Retriever - Labrador (3), Retriever (unspecified) (2), Terrier - Yorkshire (2).

Leading clinical signs: Emesis (5), Vomiting (3), Weight gain (2), Behavioural disorder NOS (1). Outcome, 16 coded reports: Outcome Unknown leads at 43.8%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.