Glucosamine ± Chondroitin

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22 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
22
Total Reports
0
Deaths Reported
0.0%
Death Rate

Active Ingredients

Glucosamine ± Chondroitin

Administration Routes

Oral

Species Affected

Dog 22

Most Affected Breeds

Retriever - Labrador 11
Crossbred Canine/dog 6
Siberian Husky 5

Most Reported Reactions

Hypoglycaemia 3
Vomiting 3
Depression 2
Skin lesion NOS 2
Appetite loss 2
Lethargy (see also Central nervous system depression in 'Neurological') 2
Cataract 2
Urinary tract infection 2
Otitis externa 2
Skin tumour NOS 2
Gingivitis 1
Smelly breath 1

Outcome Breakdown

Recovered/Normal
16 (72.7%)
Outcome Unknown
4 (18.2%)
Ongoing
2 (9.1%)

Data Summary

Metric Value
Total adverse event reports 22
Reports involving death 0
Case-fatality rate (reported events) 0.0%
Distinct species in reports 1
Distinct breeds in reports 3
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Glucosamine ± Chondroitin Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 22 adverse event reports referencing Glucosamine ± Chondroitin, including 0 reports in which the animal died — a 0.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Glucosamine ± Chondroitin. Reported administration route is Oral. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Glucosamine ± Chondroitin reports are Dog (22 reports), with Dog accounting for the largest share. Within those species, Retriever - Labrador (11), Crossbred Canine/dog (6), Siberian Husky (5) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Glucosamine ± Chondroitin are Hypoglycaemia (3), Vomiting (3), Depression (2), Skin lesion NOS (2). Of the 22 reports with a coded outcome, Recovered/Normal is the leading category at 72.7%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Glucosamine ± Chondroitin.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial