Drug profile

The FDA adverse-event record for Galliprant

985 FDA reports name Galliprant, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#184 of 2,679
by report volume (all drugs)
985
adverse-event reports
20.1%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Galliprant ranks #184 of 2679 by total reports (985) and #241 of 1130 by death-coded share (20.1%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#184
This drug, reports of 2679
#241
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Galliprant has 985 reports now versus 974 in that prior snapshot: 11 more (1.1%).

Report change
+11
Death-coded reports
+1
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Galliprant changes

Signature read: death-coded report count at 198 is the most distinctive stamp on Galliprant's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
985
Total Reports
198
Deaths Reported
20.1%
Death-coded share of reports

Active Ingredients

Galliprant

Administration Routes

UnknownOralOphthalmic

Species Affected

Dog 985

Most Affected Breeds

Retriever - Labrador 183
Shepherd Dog - German 65
Retriever - Golden 63
Crossbred Canine/dog 44
Dog (unknown) 33
Siberian Husky 32
Terrier - Bull - American Pit 31
Chihuahua 28
Collie - Border 28
Boxer (German Boxer) 25

Most Reported Reactions

Death by euthanasia 151
Lethargy (see also Central nervous system depression in Neurological) 150
Diarrhoea 95
Vomiting 85
Seizure NOS 80
Ataxia 79
Lack of efficacy - NOS 78
Urinary incontinence 74
Limb weakness 67
Anorexia 65
Not eating 64
Decreased appetite 59

Outcome Breakdown

Ongoing
571 (58.0%)
Euthanized
151 (15.3%)
Recovered/Normal
114 (11.6%)
Outcome Unknown
100 (10.2%)
Died
47 (4.8%)
Recovered with Sequela
2 (0.2%)

Galliprant: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Galliprant, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Galliprant (#184 of 2,679 by report volume); death-coded 20.1%. PlainBreed drug row · death-coded report count stamp 198 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →