Frontline

34 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

Total Reports

Deaths Reported

290.0%

Death Rate

Active Ingredients

Frontline

Administration Routes

TopicalUnknown

Species Affected

Dog 27

Cat 7

Most Affected Breeds

Retriever - Labrador 6

Domestic Shorthair 4

Domestic Longhair 2

Crossbred Canine/dog 2

Siberian Husky 2

Doberman Pinscher 2

Terrier (unspecified) 2

Spaniel - Cocker American 1

Chihuahua 1

Spitz - American Eskimo Dog 1

Most Reported Reactions

Lack of efficacy (bacteria) - Borrelia 8

Lack of efficacy (bacteria) - NOS 4

Vomiting 3

Lethargy (see also Central nervous system depression in 'Neurological') 3

Lethargy (see also Central nervous system depression in Neurological) 3

Diarrhoea 2

Anorexia 2

Weight loss 2

Hot spot (pyotraumatic dermatitis) 2

Lack of efficacy (ectoparasite) - tick NOS 2

Application site alopecia 1

Anaemia NOS 1

Outcome Breakdown

Ongoing

21 (61.8%)

Outcome Unknown

8 (23.5%)

Recovered with Sequela

2 (5.9%)

Recovered/Normal

2 (5.9%)

Euthanized

1 (2.9%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.