Drug profile

The FDA adverse-event record for Fluticasone

59 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Fluticasone. See the species affected, top reactions, and outcomes below.

59
adverse-event reports
10.2%
death-coded share
Cat
most-reported species
11
Diarrhoea - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
59
Total Reports
6
Deaths Reported
10.2%
Death Rate

Active Ingredients

Fluticasone

Administration Routes

UnknownRespiratory (Inhalation)OtherNasal

Species Affected

Cat 30
Dog 19
Human 8
Other 1
Horse 1

Most Affected Breeds

Domestic Shorthair 20
Unknown 9
Boxer (German Boxer) 3
Retriever - Labrador 3
Chihuahua 2
Spaniel - Cocker American 2
Terrier - Jack Russell 1
Terrier - Bull - American Pit 1
Terrier - Yorkshire 1
Warmblood (unspecified) 1

Most Reported Reactions

Diarrhoea 11
Abnormal radiograph finding 9
Vomiting 8
Lack of efficacy - NOS 7
Anaphylaxis 5
Other abnormal test result NOS 5
Elevated blood urea nitrogen (BUN) 5
Proteinuria 5
Lethargy (see also Central nervous system depression in Neurological) 5
Pale mucous membrane 4
Death by euthanasia 4
Moist dermatitis 4

Outcome Breakdown

Ongoing
19 (32.8%)
Recovered/Normal
16 (27.6%)
Outcome Unknown
16 (27.6%)
Euthanized
4 (6.9%)
Died
2 (3.4%)
Recovered with Sequela
1 (1.7%)

Fluticasone Adverse Event Insights

59 reports name Fluticasone; 6 recorded a death outcome (10.2% of reported events, not a population-level mortality rate). Active ingredient: Fluticasone. Administration routes: Unknown, Respiratory (Inhalation), Other, Nasal.

By species: Cat (30 reports), Dog (19 reports), Human (8 reports). By breed: Domestic Shorthair (20), Unknown (9), Boxer (German Boxer) (3).

Leading clinical signs: Diarrhoea (11), Abnormal radiograph finding (9), Vomiting (8), Lack of efficacy - NOS (7). Outcome, 58 coded reports: Ongoing leads at 32.8%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.