Drug profile

The FDA adverse-event record for Fluralaner,Moxidectin

17 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Fluralaner,Moxidectin. See the species affected, top reactions, and outcomes below.

17
adverse-event reports
11.8%
death-coded share
Cat
most-reported species
4
Lack of efficacy (endoparasite) - tapeworm - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
17
Total Reports
2
Deaths Reported
11.8%
Death Rate

Active Ingredients

Fluralaner,Moxidectin

Administration Routes

UnknownTopical

Species Affected

Cat 16
Dog 1

Most Affected Breeds

Domestic Shorthair 12
American Shorthair 2
Maine Coon 1
Coonhound (unspecified) 1
Cat (unknown) 1

Most Reported Reactions

Lack of efficacy (endoparasite) - tapeworm 4
Lethargy (see also Central nervous system depression in Neurological) 4
Vomiting 3
Vocalisation 3
Urinary bladder disorder NOS 3
Death by euthanasia 2
Urinary incontinence 2
Fever 2
Not eating 2
UNPALATABLE 2
Behavioural disorder NOS 2
Crystalluria 2

Outcome Breakdown

Outcome Unknown
7 (41.2%)
Ongoing
6 (35.3%)
Euthanized
2 (11.8%)
Recovered/Normal
2 (11.8%)

Fluralaner,Moxidectin Adverse Event Insights

17 reports name Fluralaner,Moxidectin; 2 recorded a death outcome (11.8% of reported events, not a population-level mortality rate). Active ingredient: Fluralaner,Moxidectin. Administration routes: Unknown, Topical.

By species: Cat (16 reports), Dog (1 reports). By breed: Domestic Shorthair (12), American Shorthair (2), Maine Coon (1).

Leading clinical signs: Lack of efficacy (endoparasite) - tapeworm (4), Lethargy (see also Central nervous system depression in Neurological) (4), Vomiting (3), Vocalisation (3). Outcome, 17 coded reports: Outcome Unknown leads at 41.2%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.