Drug profile

The FDA adverse-event record for Flunixin Meglumine Injectable

302 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Flunixin Meglumine Injectable. See the species affected, top reactions, and outcomes below.

302
adverse-event reports
38.1%
death-coded share
Horse
most-reported species
81
Death - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
302
Total Reports
115
Deaths Reported
38.1%
Death Rate

Active Ingredients

Flunixin Meglumine Injectable

Administration Routes

UnknownIntravenousIntramuscularSubcutaneousOralTopicalIntraocularOtherOphthalmicIntravesical

Species Affected

Horse 120
Cattle 78
Unknown 49
Human 21
Pig 8
Dog 6
Sheep 5
Goat 5
Other Equids 3
Cat 2

Most Affected Breeds

Unknown 74
Quarter Horse 37
Cattle (other) 21
Holstein-Friesian also known as Holstein 14
Aberdeen Angus 11
Crossbred Bovine/Cattle 10
Warmblood (unspecified) 9
Thoroughbred 9
Red Angus 6
Horse (unknown) 6

Most Reported Reactions

Death 81
Lack of efficacy - NOS 48
Contamination, Particulate Matter 28
Injection site swelling 23
INEFFECTIVE, ANTIINFLAMMATORY 22
Death by euthanasia 22
Colic 18
Fever 16
Injection site pain 15
Lack of efficacy (bacteria) - NOS 13
Anaphylaxis 12
Appearance, Abnormal 12

Outcome Breakdown

Died
92 (30.7%)
Recovered/Normal
81 (27.0%)
Ongoing
70 (23.3%)
Outcome Unknown
30 (10.0%)
Euthanized
24 (8.0%)
Recovered with Sequela
3 (1.0%)

Flunixin Meglumine Injectable Adverse Event Insights

302 reports name Flunixin Meglumine Injectable; 115 recorded a death outcome (38.1% of reported events, not a population-level mortality rate). Active ingredient: Flunixin Meglumine Injectable. Administration routes: Unknown, Intravenous, Intramuscular, Subcutaneous.

By species: Horse (120 reports), Cattle (78 reports), Unknown (49 reports). By breed: Unknown (74), Quarter Horse (37), Cattle (other) (21).

Leading clinical signs: Death (81), Lack of efficacy - NOS (48), Contamination, Particulate Matter (28), Injection site swelling (23). Outcome, 300 coded reports: Died leads at 30.7%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.