Drug profile

The FDA adverse-event record for Flunixin Meglumine Injectable

319 FDA reports name Flunixin Meglumine Injectable, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#399 of 2,679
by report volume (all drugs)
319
adverse-event reports
36.7%
death-coded share
Horse
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Flunixin Meglumine Injectable ranks #399 of 2679 by total reports (319) and #93 of 1130 by death-coded share (36.7%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#399
This drug, reports of 2679
#93
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Flunixin Meglumine Injectable has 319 reports now versus 312 in that prior snapshot: 7 more (2.2%).

Report change
+7
Death-coded reports
+1
Death-coded share
−0.5 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Flunixin Meglumine Injectable changes

Signature read: death-coded report count at 117 is the most distinctive stamp on Flunixin Meglumine Injectable's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
319
Total Reports
117
Deaths Reported
36.7%
Death-coded share of reports

Active Ingredients

Flunixin Meglumine Injectable

Administration Routes

UnknownIntravenousIntramuscularSubcutaneousOralTopicalIntraocularOtherOphthalmicIntravesical

Species Affected

Horse 131
Cattle 79
Unknown 53
Human 21
Pig 8
Dog 6
Sheep 6
Goat 5
Other Equids 3
Cat 2

Most Affected Breeds

Unknown 78
Quarter Horse 41
Cattle (other) 21
Holstein-Friesian also known as Holstein 14
Aberdeen Angus 12
Crossbred Bovine/Cattle 10
Warmblood (unspecified) 10
Thoroughbred 10
Horse (unknown) 7
Red Angus 6

Most Reported Reactions

Death 81
Lack of efficacy - NOS 49
Contamination, Particulate Matter 29
Injection site swelling 25
Death by euthanasia 24
INEFFECTIVE, ANTIINFLAMMATORY 22
Fever 19
Colic 19
Injection site pain 16
Anaphylaxis 14
Lack of efficacy (bacteria) - NOS 13
Other abnormal test result NOS 13

Outcome Breakdown

Died
92 (29.3%)
Recovered/Normal
86 (27.4%)
Ongoing
74 (23.6%)
Outcome Unknown
32 (10.2%)
Euthanized
26 (8.3%)
Recovered with Sequela
4 (1.3%)

Flunixin Meglumine Injectable: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Flunixin Meglumine Injectable, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

  • Compare Flunixin Meglumine Injectable's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Flunixin Meglumine Injectable (#399 of 2,679 by report volume); death-coded 36.7%. PlainBreed drug row · death-coded report count stamp 117 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →