Flumethrin/Imidacloprid

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15 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
15
Total Reports
0
Deaths Reported
0.0%
Death Rate

Active Ingredients

Flumethrin/Imidacloprid

Administration Routes

Topical

Species Affected

Dog 9
Cat 6

Most Affected Breeds

Ragdoll 3
Pointing Dog - German Short-haired 2
Domestic Shorthair 2
Boxer (German Boxer) 1
Crossbred Canine/dog 1
Retriever - Labrador 1
Spaniel - Cocker American 1
Beagle 1
Bichon Frise 1
Domestic Longhair 1

Most Reported Reactions

Lack of efficacy (ectoparasite) - flea 9
Vomiting 3
Lack of efficacy - NOS 2
Lethargy (see also Central nervous system depression in 'Neurological') 2
Intestinal disorder NOS 2
Gagging 1
Polydipsia 1
Recumbency 1
Polyuria 1
Cough 1
Proprioception abnormality 1
Respiratory tract disorder NOS 1

Outcome Breakdown

Outcome Unknown
7 (46.7%)
Ongoing
6 (40.0%)
Recovered/Normal
2 (13.3%)

Data Summary

Metric Value
Total adverse event reports 15
Reports involving death 0
Case-fatality rate (reported events) 0.0%
Distinct species in reports 2
Distinct breeds in reports 11
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Flumethrin/Imidacloprid Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 15 adverse event reports referencing Flumethrin/Imidacloprid, including 0 reports in which the animal died — a 0.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Flumethrin/Imidacloprid. Reported administration route is Topical. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Flumethrin/Imidacloprid reports are Dog (9 reports), Cat (6 reports), with Dog accounting for the largest share. Within those species, Ragdoll (3), Pointing Dog - German Short-haired (2), Domestic Shorthair (2) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Flumethrin/Imidacloprid are Lack of efficacy (ectoparasite) - flea (9), Vomiting (3), Lack of efficacy - NOS (2), Lethargy (see also Central nervous system depression in 'Neurological') (2). Of the 15 reports with a coded outcome, Outcome Unknown is the leading category at 46.7%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Flumethrin/Imidacloprid.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial