Drug profile

The FDA adverse-event record for Flumethrin-Imidacloprid

975 FDA reports name Flumethrin-Imidacloprid, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#185 of 2,679
by report volume (all drugs)
975
adverse-event reports
4.1%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Flumethrin-Imidacloprid ranks #185 of 2679 by total reports (975) and #838 of 1130 by death-coded share (4.1%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#185
This drug, reports of 2679
#838
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Flumethrin-Imidacloprid has 975 reports now versus 975 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Flumethrin-Imidacloprid changes

Signature read: 975 reports place Flumethrin-Imidacloprid in the upper third of FDA AER volume (#185 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
975
Total Reports
40
Deaths Reported
4.1%
Death-coded share of reports

Active Ingredients

Flumethrin-Imidacloprid

Administration Routes

TopicalUnknownOralOther

Species Affected

Dog 613
Cat 361
Human 1

Most Affected Breeds

Domestic Shorthair 219
Retriever - Labrador 51
Domestic Longhair 48
Crossbred Canine/dog 40
Cat (unknown) 38
Terrier - Yorkshire 36
Chihuahua 35
Dog (unknown) 35
Shepherd Dog - German 32
Domestic Mediumhair 26

Most Reported Reactions

Lack of efficacy (ectoparasite) - flea 341
Pruritus 261
Lethargy (see also Central nervous system depression in 'Neurological') 132
Application site pruritus 122
Application site alopecia 119
Application site erythema 90
Behavioural disorder NOS 86
Anorexia 63
Vomiting 59
Application site lesion 55
Application site scab 49
Skin lesion NOS 46

Outcome Breakdown

Outcome Unknown
651 (66.8%)
Recovered/Normal
278 (28.5%)
Died
21 (2.2%)
Euthanized
19 (1.9%)
Ongoing
5 (0.5%)
Recovered with Sequela
1 (0.1%)

Flumethrin-Imidacloprid: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Flumethrin-Imidacloprid, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar report volume

Nearest other drugs by FDA report count (975 here).

Similar death-coded share

Nearest other drugs by death-coded share (4.1% here), distinct from the volume row.

What to do with this drug

  • Compare Flumethrin-Imidacloprid's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Flumethrin-Imidacloprid (#185 of 2,679 by report volume); death-coded 4.1%. PlainBreed drug row · report volume stamp 975 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →