Drug profile

The FDA adverse-event record for Fluid Solution

20 FDA reports name Fluid Solution, a lower-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#1794 of 2,679
by report volume (all drugs)
20
adverse-event reports
10.0%
death-coded share
Cat
most-reported species
Verify with FDA CVM →

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Fluid Solution ranks #1778 of 2679 by total reports (20). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1778
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Fluid Solution has 20 reports now versus 20 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Fluid Solution changes

Signature read: report volume at 20 is the most distinctive stamp on Fluid Solution's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
20
Total Reports
2
Deaths Reported
10.0%
Death-coded share of reports

Active Ingredients

Fluid Solution

Administration Routes

SubcutaneousIntravenousUnknown

Species Affected

Cat 11
Dog 9

Most Affected Breeds

Domestic Shorthair 7
Chihuahua 2
Collie - Border 2
Mixed (Dog) 1
Bengal 1
Crossbred Canine/dog 1
Tonkinese 1
Maine Coon 1
Poodle - Miniature 1
Shepherd Dog - German 1

Most Reported Reactions

Anorexia 11
Lethargy (see also Central nervous system depression in 'Neurological') 9
Ataxia 6
Weight loss 5
Other abnormal test result NOS 4
Adipsia 4
Abnormal radiograph finding 4
Seizure NOS 4
Behavioural disorder NOS 3
Elevated blood urea nitrogen (BUN) 3
Hypersalivation 3
Dyspnoea 3

Outcome Breakdown

Outcome Unknown
10 (50.0%)
Recovered/Normal
5 (25.0%)
Ongoing
3 (15.0%)
Euthanized
1 (5.0%)
Died
1 (5.0%)

Fluid Solution: lower report volume in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Fluid Solution (#1794 of 2,679 by report volume); death-coded 10.0%. PlainBreed drug row · report volume stamp 20 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →