Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate

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1,197 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
1,197
Total Reports
27
Deaths Reported
230.0%
Death Rate

Active Ingredients

Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate

Administration Routes

UnknownAuricular (Otic)OtherTopicalOral

Species Affected

Unknown 589
Dog 471
Cat 117
Human 19
Rabbit 1

Most Affected Breeds

Unknown 608
Domestic Shorthair 70
Retriever - Labrador 62
Dog (unknown) 53
Retriever - Golden 32
Shih Tzu 25
Spaniel - Cocker American 22
Pit Bull 19
Crossbred Canine/dog 19
Pug 17

Most Reported Reactions

Tubes, Leaking 439
Lack of efficacy - NOS 124
Ataxia 114
Odor, Abnormal 79
Anorexia 75
Ear discharge 63
Head tilt - ear disorder 63
Head shake - ear disorder 62
Lethargy (see also Central nervous system depression in 'Neurological') 55
Nystagmus 50
Behavioural disorder NOS 44
Underfilling, Package 44

Outcome Breakdown

Outcome Unknown
369 (60.7%)
Recovered/Normal
206 (33.9%)
Died
14 (2.3%)
Euthanized
13 (2.1%)
Recovered with Sequela
6 (1.0%)

Data Summary

Metric Value
Total adverse event reports 1,197
Reports involving death 27
Case-fatality rate (reported events) 230.0%
Distinct species in reports 5
Distinct breeds in reports 20
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 1,197 adverse event reports referencing Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate, including 27 reports in which the animal died — a 230.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate. Reported administration routes include Unknown, Auricular (Otic), Other, Topical. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate reports are Unknown (589 reports), Dog (471 reports), Cat (117 reports), with Unknown accounting for the largest share. Within those species, Unknown (608), Domestic Shorthair (70), Retriever - Labrador (62) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate are Tubes, Leaking (439), Lack of efficacy - NOS (124), Ataxia (114), Odor, Abnormal (79). Of the 608 reports with a coded outcome, Outcome Unknown is the leading category at 60.7%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial