Florfenicol, Terbinafine, Betamethasone Acetate
557 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
557
Total Reports
24
Deaths Reported
430.0%
Death Rate
Active Ingredients
Florfenicol, Terbinafine, Betamethasone Acetate
Administration Routes
Auricular (Otic)UnknownOphthalmicTopicalOralOther
Species Affected
Dog 419
Cat 112
Unknown 18
Human 8
Most Affected Breeds
Domestic Shorthair 75
Retriever - Labrador 45
Unknown 26
Shih Tzu 23
Chihuahua 21
Dog (unknown) 21
Maltese 20
Bulldog - French 18
Terrier - Yorkshire 17
Retriever - Golden 16
Most Reported Reactions
Deafness 79
Lack of efficacy - NOS 56
Vomiting 45
Head shake - ear disorder 43
Not eating 41
Lethargy (see also Central nervous system depression in 'Neurological') 40
Loss of hearing 38
Head tilt - ear disorder 37
Ataxia 37
Corneal ulcer 34
Horner's syndrome 31
Ear discharge 31
Outcome Breakdown
Outcome Unknown
299 (55.3%)
Recovered/Normal
136 (25.1%)
Ongoing
63 (11.6%)
Recovered with Sequela
19 (3.5%)
Euthanized
13 (2.4%)
Died
11 (2.0%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.