Drug profile

The FDA adverse-event record for Fish Oil Supplement

108 FDA reports name Fish Oil Supplement, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#751 of 2,679
by report volume (all drugs)
108
adverse-event reports
6.5%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Fish Oil Supplement ranks #749 of 2679 by total reports (108) and #716 of 1130 by death-coded share (6.5%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#749
This drug, reports of 2679
#716
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Fish Oil Supplement has 108 reports now versus 99 in that prior snapshot: 9 more (9.1%).

Report change
+9
Death-coded reports
+1
Death-coded share
+0.4 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Fish Oil Supplement changes

Signature read: 108 reports place Fish Oil Supplement in the upper third of FDA AER volume (#751 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
108
Total Reports
7
Deaths Reported
6.5%
Death-coded share of reports

Active Ingredients

Fish Oil Supplement

Administration Routes

OralUnknown

Species Affected

Dog 103
Cat 3
Human 2

Most Affected Breeds

Retriever - Labrador 18
Retriever - Golden 17
Collie - Border 6
Shepherd Dog - Australian 6
Shepherd Dog - German 5
Domestic Shorthair 3
Terrier - Bull - American Pit 3
Crossbred Canine/dog 2
Chihuahua 2
Dog (other) 2

Most Reported Reactions

Diarrhoea 14
Other abnormal test result NOS 12
Lethargy (see also Central nervous system depression in 'Neurological') 11
Vomiting 10
Anorexia 9
Urinary incontinence 8
Lack of efficacy - NOS 8
Abnormal radiograph finding 8
Inappropriate urination 7
Lameness 6
Emesis 6
Weight loss 6

Outcome Breakdown

Ongoing
51 (47.2%)
Recovered/Normal
32 (29.6%)
Outcome Unknown
17 (15.7%)
Died
4 (3.7%)
Euthanized
3 (2.8%)
Recovered with Sequela
1 (0.9%)

Fish Oil Supplement: high report volume in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Fish Oil Supplement, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Fish Oil Supplement (#751 of 2,679 by report volume); death-coded 6.5%. PlainBreed drug row · report volume stamp 108 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →