Drug profile

The FDA adverse-event record for Firocoxib 57 Mg Chewable

518 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Firocoxib 57 Mg Chewable. See the species affected, top reactions, and outcomes below.

518
adverse-event reports
12.0%
death-coded share
Dog
most-reported species
130
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
518
Total Reports
62
Deaths Reported
12.0%
Death Rate

Active Ingredients

Firocoxib 57 Mg Chewable

Administration Routes

OralUnknownSubcutaneousOther

Species Affected

Dog 367
Unknown 112
Horse 32
Cat 4
Human 3

Most Affected Breeds

Unknown 120
Crossbred Canine/dog 30
Dog (unknown) 22
Shih Tzu 20
Schnauzer - Miniature 14
Spaniel - Cocker American 14
Dachshund (unspecified) 13
Chihuahua 13
Terrier - Jack Russell 12
Pug 11

Most Reported Reactions

Vomiting 130
Other abnormal test result NOS 86
Lethargy (see also Central nervous system depression in 'Neurological') 66
Diarrhoea 49
Elevated blood urea nitrogen (BUN) 46
Anorexia 46
Elevated creatinine 35
Elevated alanine aminotransferase (ALT) 35
Not eating 33
Death 32
Elevated serum alkaline phosphatase (SAP) 30
Containers, Damaged 27

Outcome Breakdown

Outcome Unknown
206 (50.6%)
Recovered/Normal
92 (22.6%)
Ongoing
44 (10.8%)
Died
35 (8.6%)
Euthanized
27 (6.6%)
Recovered with Sequela
3 (0.7%)

Firocoxib 57 Mg Chewable Adverse Event Insights

518 reports name Firocoxib 57 Mg Chewable; 62 recorded a death outcome (12.0% of reported events, not a population-level mortality rate). Active ingredient: Firocoxib 57 Mg Chewable. Administration routes: Oral, Unknown, Subcutaneous, Other.

By species: Dog (367 reports), Unknown (112 reports), Horse (32 reports). By breed: Unknown (120), Crossbred Canine/dog (30), Dog (unknown) (22).

Leading clinical signs: Vomiting (130), Other abnormal test result NOS (86), Lethargy (see also Central nervous system depression in 'Neurological') (66), Diarrhoea (49). Outcome, 407 coded reports: Outcome Unknown leads at 50.6%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.