Drug profile

The FDA adverse-event record for Firocoxib 227 Mg Chewable

1,000 FDA reports name Firocoxib 227 Mg Chewable, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#181 of 2,679
by report volume (all drugs)
1,000
adverse-event reports
16.6%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Firocoxib 227 Mg Chewable ranks #181 of 2679 by total reports (1,000) and #317 of 1130 by death-coded share (16.6%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#181
This drug, reports of 2679
#317
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Firocoxib 227 Mg Chewable has 1,000 reports now versus 1,000 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Firocoxib 227 Mg Chewable changes

Signature read: death-coded report count at 166 is the most distinctive stamp on Firocoxib 227 Mg Chewable's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
1,000
Total Reports
166
Deaths Reported
16.6%
Death-coded share of reports

Active Ingredients

Firocoxib 227 Mg Chewable

Administration Routes

OralUnknownTopical

Species Affected

Dog 833
Unknown 138
Horse 17
Cat 8
Human 4

Most Affected Breeds

Retriever - Labrador 175
Unknown 148
Crossbred Canine/dog 81
Dog (other) 70
Shepherd Dog - German 61
Retriever - Golden 53
Dog (unknown) 46
Boxer (German Boxer) 45
Rottweiler 27
Mastiff 19

Most Reported Reactions

Vomiting 294
Other abnormal test result NOS 244
Lethargy (see also Central nervous system depression in 'Neurological') 146
Elevated blood urea nitrogen (BUN) 145
Elevated creatinine 117
Elevated serum alkaline phosphatase (SAP) 92
Death 90
Anorexia 83
Diarrhoea 78
Elevated alanine aminotransferase (ALT) 74
Death by euthanasia 73
Not eating 62

Outcome Breakdown

Outcome Unknown
424 (49.1%)
Recovered/Normal
162 (18.8%)
Ongoing
105 (12.2%)
Died
94 (10.9%)
Euthanized
72 (8.3%)
Recovered with Sequela
6 (0.7%)

Firocoxib 227 Mg Chewable: high report volume in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Firocoxib 227 Mg Chewable, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

  • Compare Firocoxib 227 Mg Chewable's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Firocoxib 227 Mg Chewable (#181 of 2,679 by report volume); death-coded 16.6%. PlainBreed drug row · death-coded report count stamp 166 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →