Drug profile

The FDA adverse-event record for Feline Leukemia

61 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Feline Leukemia. Species, reactions, and outcomes follow.

#1007 of 2,679
by report volume (all drugs)
61
adverse-event reports
3.3%
death-coded share
Cat
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Feline Leukemia ranks #1004 of 2679 by total reports (61) and #894 of 1130 by death-coded share (3.3%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1004
This drug, reports of 2679
#894
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Feline Leukemia has 61 reports now versus 61 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Feline Leukemia changes

Signature read: Feline Leukemia's 3.3% death-coded share is among the lowest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
61
Total Reports
2
Deaths Reported
3.3%
Death-coded share of reports

Active Ingredients

Feline Leukemia

Administration Routes

SubcutaneousUnknownIntramuscularParenteral

Species Affected

Cat 61

Most Affected Breeds

Domestic Shorthair 43
Domestic Longhair 8
Domestic Mediumhair 4
Cat (unknown) 2
Ragdoll 1
Maine Coon 1
Turkish Van 1
Siamese 1

Most Reported Reactions

Application site alopecia 25
Lethargy (see also Central nervous system depression in 'Neurological') 16
Ataxia 11
Anorexia 10
Hypersalivation 8
Application site pruritus 8
Behavioural disorder NOS 6
Emesis 5
Adipsia 5
Application site erythema 5
Muscle tremor 4
Diarrhoea 4

Outcome Breakdown

Outcome Unknown
35 (57.4%)
Recovered/Normal
23 (37.7%)
Euthanized
2 (3.3%)
Ongoing
1 (1.6%)

Feline Leukemia: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Nationwide drugs with similar profiles

Two openFDA-derived peer sets for Feline Leukemia, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Feline Leukemia (#1007 of 2,679 by report volume); death-coded 3.3%. PlainBreed drug row · death-coded share stamp 3.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →