Drug profile

The FDA adverse-event record for Febantel + Praziquantel + Pyrantel Embonate

28 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Febantel + Praziquantel + Pyrantel Embonate. See the species affected, top reactions, and outcomes below.

28
adverse-event reports
3.6%
death-coded share
Dog
most-reported species
12
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
28
Total Reports
1
Deaths Reported
3.6%
Death Rate

Active Ingredients

FebantelPraziquantelPyrantel Embonate

Administration Routes

OralUnknown

Species Affected

Dog 28

Most Affected Breeds

Retriever - Labrador 4
Greyhound 3
Chihuahua 2
Schnauzer - Miniature 2
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 2
Havanese 2
Shar Pei 1
Crossbred Canine/dog 1
Doberman Pinscher 1
Shih Tzu 1

Most Reported Reactions

Vomiting 12
Diarrhoea 6
Lack of efficacy (endoparasite) - roundworm NOS 6
Lack of efficacy (endoparasite) - NOS 5
Lack of efficacy (endoparasite) - tapeworm 5
Lack of efficacy (endoparasite) - hookworm 3
Loose stool 2
Other abnormal test result NOS 2
Appetite loss 2
Lethargy (see also Central nervous system depression in 'Neurological') 2
Emesis (multiple) 2
Respiratory distress 1

Outcome Breakdown

Outcome Unknown
17 (60.7%)
Recovered/Normal
8 (28.6%)
Ongoing
2 (7.1%)
Euthanized
1 (3.6%)

Febantel + Praziquantel + Pyrantel Embonate Adverse Event Insights

28 reports name Febantel + Praziquantel + Pyrantel Embonate; 1 recorded a death outcome (3.6% of reported events, not a population-level mortality rate). Active ingredients: Febantel, Praziquantel, Pyrantel Embonate. Administration routes: Oral, Unknown.

By species: Dog (28 reports). By breed: Retriever - Labrador (4), Greyhound (3), Chihuahua (2).

Leading clinical signs: Vomiting (12), Diarrhoea (6), Lack of efficacy (endoparasite) - roundworm NOS (6), Lack of efficacy (endoparasite) - NOS (5). Outcome, 28 coded reports: Outcome Unknown leads at 60.7%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.