Drug profile

The FDA adverse-event record for Eye Ointment (Unknown)

81 FDA reports name Eye Ointment (Unknown), a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#866 of 2,679
by report volume (all drugs)
81
adverse-event reports
3.7%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Eye Ointment (Unknown) ranks #866 of 2679 by total reports (81) and #865 of 1130 by death-coded share (3.7%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#866
This drug, reports of 2679
#865
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Eye Ointment (Unknown) has 81 reports now versus 79 in that prior snapshot: 2 more (2.5%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Eye Ointment (Unknown) changes

Signature read: Eye Ointment (Unknown)'s 3.7% death-coded share is among the lowest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
81
Total Reports
3
Deaths Reported
3.7%
Death-coded share of reports

Active Ingredients

Eye Ointment (Unknown)

Administration Routes

UnknownOphthalmicIntraocularOralAuricular (Otic)

Species Affected

Dog 69
Cat 12

Most Affected Breeds

Shih Tzu 6
Dachshund (unspecified) 6
Retriever - Labrador 5
Crossbred Canine/dog 5
Domestic Shorthair 5
Bichon Frise 4
Spaniel - Cocker American 4
Terrier - Jack Russell 3
Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne)) 3
Cat (unknown) 3

Most Reported Reactions

Emesis 23
Vomiting 18
Diarrhoea 11
Lack of efficacy - NOS 9
Lethargy (see also Central nervous system depression in 'Neurological') 9
Behavioural disorder NOS 9
Corneal ulcer 8
Other abnormal test result NOS 7
Decreased appetite 6
Lack of efficacy (ectoparasite) - flea 6
Neurogenic keratoconjunctivitis sicca (KCS) 6
Scratching 5

Outcome Breakdown

Recovered/Normal
37 (45.7%)
Outcome Unknown
25 (30.9%)
Ongoing
9 (11.1%)
Recovered with Sequela
7 (8.6%)
Euthanized
2 (2.5%)
Died
1 (1.2%)

Eye Ointment (Unknown): low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Eye Ointment (Unknown), both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

  • Compare Eye Ointment (Unknown)'s report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Eye Ointment (Unknown) (#866 of 2,679 by report volume); death-coded 3.7%. PlainBreed drug row · death-coded share stamp 3.7% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →