Drug profile

The FDA adverse-event record for Eye Medication (Unknown)

56 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Eye Medication (Unknown). Species, reactions, and outcomes follow.

#1046 of 2,679
by report volume (all drugs)
56
adverse-event reports
7.1%
death-coded share
Dog
most-reported species
Verify with FDA CVM →

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Eye Medication (Unknown) ranks #1044 of 2679 by total reports (56) and #688 of 1130 by death-coded share (7.1%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1044
This drug, reports of 2679
#688
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Eye Medication (Unknown) has 56 reports now versus 55 in that prior snapshot: 1 more (1.8%).

Report change
+1
Death-coded reports
+1
Death-coded share
+1.7 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Eye Medication (Unknown) changes

Signature read: death-coded share at 7.1% is the most distinctive stamp on Eye Medication (Unknown)'s FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
56
Total Reports
4
Deaths Reported
7.1%
Death-coded share of reports

Active Ingredients

Eye Medication (Unknown)

Administration Routes

UnknownOphthalmicIntraocularTopicalParenteral

Species Affected

Dog 42
Cat 14

Most Affected Breeds

Domestic Shorthair 8
Shih Tzu 4
Retriever - Labrador 3
Poodle - Miniature 3
Bulldog - English 3
Havanese 2
Dachshund (unspecified) 2
Poodle (unspecified) 2
Cat (unknown) 2
Terrier - Irish Soft-coated Wheaten 2

Most Reported Reactions

Corneal ulcer 16
Ocular discharge 13
Behavioural disorder NOS 10
Eye disorder NOS (for Photophobia see neurological) 9
Not eating 8
Vomiting 7
Neurogenic keratoconjunctivitis sicca (KCS) 7
Conjunctivitis 6
Dry eye 6
Ear infection NOS 6
Lethargy (see also Central nervous system depression in 'Neurological') 5
Facial paralysis 5

Outcome Breakdown

Ongoing
27 (48.2%)
Outcome Unknown
15 (26.8%)
Recovered/Normal
10 (17.9%)
Euthanized
3 (5.4%)
Died
1 (1.8%)

Eye Medication (Unknown) Adverse Event Insights

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Nationwide drugs with similar profiles

Two openFDA-derived peer sets for Eye Medication (Unknown), both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar death-coded share

Nearest other drugs by death-coded share (7.1% here), distinct from the volume row.

Ranitidine 7.1% Oclacitinib 7.2% Bordetella Bronchiseptica 92B 012992-7 Strain Boehringer Ingelheim;Canine Adenov 7.2% Ivermectin 1% Injection 7.1%

What to do with this drug

  • Compare Eye Medication (Unknown)'s report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Eye Medication (Unknown) (#1046 of 2,679 by report volume); death-coded 7.1%. PlainBreed drug row · death-coded share stamp 7.1% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →