Drug profile

The FDA adverse-event record for Eye Lubricant

57 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Eye Lubricant. Species, reactions, and outcomes follow.

#1040 of 2,679
by report volume (all drugs)
57
adverse-event reports
8.8%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Eye Lubricant ranks #1035 of 2679 by total reports (57) and #605 of 1130 by death-coded share (8.8%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1035
This drug, reports of 2679
#605
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Eye Lubricant has 57 reports now versus 54 in that prior snapshot: 3 more (5.6%).

Report change
+3
Death-coded reports
+0
Death-coded share
−0.5 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Eye Lubricant changes

Signature read: report volume at 57 is the most distinctive stamp on Eye Lubricant's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
57
Total Reports
5
Deaths Reported
8.8%
Death-coded share of reports

Active Ingredients

Eye Lubricant

Administration Routes

UnknownOphthalmicIntraocularOtherTopical

Species Affected

Dog 53
Cat 4

Most Affected Breeds

Shih Tzu 8
Schnauzer (unspecified) 6
Bulldog - French 5
Crossbred Canine/dog 4
Domestic Shorthair 4
Terrier - Rat 4
Pug 3
Chihuahua 3
Maltese 3
Terrier - Yorkshire 2

Most Reported Reactions

Keratoconjunctivitis sicca 17
Corneal ulcer 16
Dry nose 14
Ocular discharge 13
Corneal disorder NOS 13
Schirmer tear test 12
Other abnormal test result NOS 11
Vomiting 11
Lethargy (see also Central nervous system depression in 'Neurological') 11
Dry eye 10
Lack of efficacy - NOS 9
Ear discharge 9

Outcome Breakdown

Outcome Unknown
24 (42.1%)
Ongoing
17 (29.8%)
Recovered/Normal
10 (17.5%)
Euthanized
5 (8.8%)
Recovered with Sequela
1 (1.8%)

Eye Lubricant Adverse Event Insights

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Nationwide drugs with similar profiles

Two openFDA-derived peer sets for Eye Lubricant, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar report volume

Nearest other drugs by FDA report count (57 here).

Similar death-coded share

Nearest other drugs by death-coded share (8.8% here), distinct from the volume row.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Eye Lubricant (#1040 of 2,679 by report volume); death-coded 8.8%. PlainBreed drug row · report volume stamp 57 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →