Drug profile

The FDA adverse-event record for Ethylene Diamine Tetra Acetic Acid Tris

24 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Ethylene Diamine Tetra Acetic Acid Tris. See the species affected, top reactions, and outcomes below.

24
adverse-event reports
0.0%
death-coded share
Dog
most-reported species
10
Lack of efficacy - NOS - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
24
Total Reports
0
Deaths Reported
0.0%
Death Rate

Active Ingredients

Ethylene Diamine Tetra Acetic Acid Tris

Administration Routes

UnknownAuricular (Otic)Other

Species Affected

Dog 22
Cat 2

Most Affected Breeds

Retriever - Labrador 3
Shepherd Dog - German 2
Pug 2
Shih Tzu 2
Retriever - Golden 2
Spaniel - Cocker English 1
Terrier - West Highland White 1
Dachshund - Miniature 1
Domestic Shorthair 1
Maltese 1

Most Reported Reactions

Lack of efficacy - NOS 10
Ear discharge 6
Ataxia 4
Deafness 3
Lethargy (see also Central nervous system depression in 'Neurological') 3
Other abnormal test result NOS 3
Ear canal inflammation 3
Ear pain 3
Impaired hearing 2
Polydipsia 2
Emesis (multiple) 2
Dry eye 2

Outcome Breakdown

Outcome Unknown
14 (58.3%)
Recovered/Normal
8 (33.3%)
Ongoing
2 (8.3%)

Ethylene Diamine Tetra Acetic Acid Tris Adverse Event Insights

24 reports name Ethylene Diamine Tetra Acetic Acid Tris; 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). Active ingredient: Ethylene Diamine Tetra Acetic Acid Tris. Administration routes: Unknown, Auricular (Otic), Other.

By species: Dog (22 reports), Cat (2 reports). By breed: Retriever - Labrador (3), Shepherd Dog - German (2), Pug (2).

Leading clinical signs: Lack of efficacy - NOS (10), Ear discharge (6), Ataxia (4), Deafness (3). Outcome, 24 coded reports: Outcome Unknown leads at 58.3%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.