Estradiol, Trenbolone Acetate

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134 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
134
Total Reports
28
Deaths Reported
2090.0%
Death Rate

Active Ingredients

Estradiol, Trenbolone Acetate

Administration Routes

UnknownSubcutaneousOral

Species Affected

Cattle 77
Unknown 55
Human 1
Dog 1

Most Affected Breeds

Unknown 56
Cattle (unknown) 28
Crossbred Bovine/Cattle 18
Holstein-Friesian also known as Holstein 13
Aberdeen Angus 12
Mixed (Cattle) 2
Beefmaster 2
Cattle (other) 1
Cattle (unspecified) 1
Dog (other) 1

Most Reported Reactions

Death 26
Increased sexual interest 24
Implant, Abnormal 23
Underfilling, Package 14
Color, Abnormal 13
Anaphylaxis 11
Dispenser, Abnormal 11
Behavioural disorder NOS 7
INEFFECTIVE, WEIGHT INC 5
Caps, Abnormal 4
Recumbency 4
Collapse (see also 'Cardio-vascular' and 'Systemic disorders') 4

Outcome Breakdown

Died
28 (84.8%)
Outcome Unknown
3 (9.1%)
Ongoing
1 (3.0%)
Recovered/Normal
1 (3.0%)

Data Summary

Metric Value
Total adverse event reports 134
Reports involving death 28
Case-fatality rate (reported events) 2090.0%
Distinct species in reports 4
Distinct breeds in reports 10
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Estradiol, Trenbolone Acetate Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 134 adverse event reports referencing Estradiol, Trenbolone Acetate, including 28 reports in which the animal died — a 2090.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Estradiol, Trenbolone Acetate. Reported administration routes include Unknown, Subcutaneous, Oral. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Estradiol, Trenbolone Acetate reports are Cattle (77 reports), Unknown (55 reports), Human (1 reports), with Cattle accounting for the largest share. Within those species, Unknown (56), Cattle (unknown) (28), Crossbred Bovine/Cattle (18) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Estradiol, Trenbolone Acetate are Death (26), Increased sexual interest (24), Implant, Abnormal (23), Underfilling, Package (14). Of the 33 reports with a coded outcome, Died is the leading category at 84.8%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Estradiol, Trenbolone Acetate.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial