Drug profile

The FDA adverse-event record for Estradiol + Trenbolone

32 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Estradiol + Trenbolone. See the species affected, top reactions, and outcomes below.

32
adverse-event reports
50.0%
death-coded share
Cattle
most-reported species
11
Death - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
32
Total Reports
16
Deaths Reported
50.0%
Death Rate

Active Ingredients

EstradiolTrenbolone

Administration Routes

SubcutaneousUnknownOtherIntra-Articular

Species Affected

Cattle 21
Unknown 10
Human 1

Most Affected Breeds

Unknown 11
Crossbred Bovine/Cattle 10
Cattle (unknown) 7
Mixed (Cattle) 2
Red Angus 1
Aberdeen Angus 1

Most Reported Reactions

Death 11
Injection site swelling 11
Respiratory tract disorder NOS 10
Decreased appetite 10
Weight loss 8
Behavioural disorder NOS 3
Potency, Low 3
Implant, Abnormal 3
NT - chronic (broncho)pneumonia/pleuropneumonia 3
Appearance, Abnormal 3
INEFFECTIVE, WEIGHT INC 2
DEATH-TREATMENT FAILURE 2

Outcome Breakdown

Died
16 (37.2%)
Ongoing
13 (30.2%)
Recovered/Normal
10 (23.3%)
Outcome Unknown
4 (9.3%)

Estradiol + Trenbolone Adverse Event Insights

32 reports name Estradiol + Trenbolone; 16 recorded a death outcome (50.0% of reported events, not a population-level mortality rate). Active ingredients: Estradiol, Trenbolone. Administration routes: Subcutaneous, Unknown, Other, Intra-Articular.

By species: Cattle (21 reports), Unknown (10 reports), Human (1 reports). By breed: Unknown (11), Crossbred Bovine/Cattle (10), Cattle (unknown) (7).

Leading clinical signs: Death (11), Injection site swelling (11), Respiratory tract disorder NOS (10), Decreased appetite (10). Outcome, 43 coded reports: Died leads at 37.2%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.