Drug profile

The FDA adverse-event record for Equine Influenza Virus, Killed Virus + Equine Rhinopneumonitis Virus, Killed Virus

40 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Equine Influenza Virus, Killed Virus + Equine Rhinopneumonitis Virus, Killed Virus. Species, reactions, and outcomes follow.

#1249 of 2,679
by report volume (all drugs)
40
adverse-event reports
17.5%
death-coded share
Horse
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Equine Influenza Virus, Killed Virus + Equine Rhinopneumonitis Virus, Killed Virus ranks #1245 of 2679 by total reports (40). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1245
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Equine Influenza Virus, Killed Virus + Equine Rhinopneumonitis Virus, Killed Virus has 40 reports now versus 39 in that prior snapshot: 1 more (2.6%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.4 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Equine Influenza Virus, Killed Virus + Equine Rhinopneumonitis Virus, Killed Virus changes

Signature read: Equine Influenza Virus, Killed Virus + Equine Rhinopneumonitis Virus, Killed Virus's 17.5% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
40
Total Reports
7
Deaths Reported
17.5%
Death-coded share of reports

Active Ingredients

Equine Influenza Virus, Killed VirusEquine Rhinopneumonitis Virus, Killed Virus

Administration Routes

IntramuscularUnknownNasal

Species Affected

Horse 40

Most Affected Breeds

Quarter Horse 13
Horse (unknown) 4
Arab 4
Thoroughbred 3
Pura Raza Española (Andalusian) 3
Miniature 2
Paint 2
Saddlebred - American 1
Crossbred Equine/horse 1
Welsh Mountain Pony 1

Most Reported Reactions

Lack of efficacy - NOS 9
Fever 6
Other abnormal test result NOS 6
Colic 6
Anorexia 6
Depression 5
Injection site pain 4
Nasal discharge 4
Death by euthanasia 4
Injection site swelling 3
Lameness 3
Rolling 3

Outcome Breakdown

Recovered/Normal
21 (51.2%)
Outcome Unknown
9 (22.0%)
Euthanized
4 (9.8%)
Ongoing
4 (9.8%)
Died
3 (7.3%)

Equine Influenza Virus, Killed Virus + Equine Rhinopneumonitis Virus, Killed Virus: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Equine Influenza Virus, Killed Virus + Equine Rhinopneumonitis Virus, Killed Virus (#1249 of 2,679 by report volume); death-coded 17.5%. PlainBreed drug row · death-coded share stamp 17.5% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →