Drug profile

The FDA adverse-event record for Entyce

138 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Entyce. See the species affected, top reactions, and outcomes below.

138
adverse-event reports
46.4%
death-coded share
Dog
most-reported species
53
Death by euthanasia - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
138
Total Reports
64
Deaths Reported
46.4%
Death Rate

Active Ingredients

Entyce

Administration Routes

OralUnknown

Species Affected

Dog 136
Cat 2

Most Affected Breeds

Retriever - Labrador 14
Shih Tzu 12
Retriever - Golden 10
Terrier - Yorkshire 9
Chihuahua 7
Terrier (unspecified) 6
Spitz - German Pomeranian 6
Dog (unknown) 5
Bulldog - French 4
Crossbred Canine/dog 4

Most Reported Reactions

Death by euthanasia 53
Lethargy (see also Central nervous system depression in Neurological) 48
Vomiting 40
Not eating 36
Diarrhoea 30
Anorexia 23
Decreased appetite 23
Elevated serum alkaline phosphatase (ALP) 21
Weight loss 20
Seizure NOS 19
Elevated alanine aminotransferase (ALT) 19
Leucocytosis NOS 16

Outcome Breakdown

Ongoing
59 (42.8%)
Euthanized
53 (38.4%)
Died
11 (8.0%)
Outcome Unknown
8 (5.8%)
Recovered/Normal
7 (5.1%)

Entyce Adverse Event Insights

138 reports name Entyce; 64 recorded a death outcome (46.4% of reported events, not a population-level mortality rate). Active ingredient: Entyce. Administration routes: Oral, Unknown.

By species: Dog (136 reports), Cat (2 reports). By breed: Retriever - Labrador (14), Shih Tzu (12), Retriever - Golden (10).

Leading clinical signs: Death by euthanasia (53), Lethargy (see also Central nervous system depression in Neurological) (48), Vomiting (40), Not eating (36). Outcome, 138 coded reports: Ongoing leads at 42.8%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.