Drug profile

The FDA adverse-event record for Enterococcus Faecium, Streptococcus Thermophilus, Lactobacillus Acidophilus, Lactobacillus Bulgaricus, Lactobacillus Casei, Bifidobacterium Bifidum, And Lactobacillus Plantarum

12 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Enterococcus Faecium, Streptococcus Thermophilus, Lactobacillus Acidophilus, Lactobacillus Bulgaricus, Lactobacillus Casei, Bifidobacterium Bifidum, And Lactobacillus Plantarum. See the species affected, top reactions, and outcomes below.

12
adverse-event reports
25.0%
death-coded share
Dog
most-reported species
9
Diarrhoea - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
12
Total Reports
3
Deaths Reported
25.0%
Death Rate

Active Ingredients

Enterococcus Faecium, Streptococcus Thermophilus, Lactobacillus Acidophilus, Lactobacillus Bulgaricus, Lactobacillus Casei, Bifidobacterium Bifidum, And Lactobacillus Plantarum

Administration Routes

Unknown

Species Affected

Dog 12

Most Affected Breeds

Retriever - Labrador 4
Chihuahua 1
Unknown 1
Boxer (German Boxer) 1
Dog (other) 1
Shih Tzu 1
Retriever - Golden 1
Terrier - Jack Russell 1
Sheepdog - Shetland 1

Most Reported Reactions

Diarrhoea 9
Vomiting 7
Decreased appetite 3
Lethargy (see also Central nervous system depression in 'Neurological') 3
Death by euthanasia 2
Abnormal ultrasound finding 2
Dehydration 2
Proteinuria 2
Partial anorexia 2
Anorexia 2
Weakness 2
Bloody diarrhoea 2

Outcome Breakdown

Ongoing
4 (33.3%)
Recovered/Normal
3 (25.0%)
Euthanized
2 (16.7%)
Outcome Unknown
2 (16.7%)
Died
1 (8.3%)

Enterococcus Faecium, Streptococcus Thermophilus, Lactobacillus Acidophilus, Lactobacillus Bulgaricus, Lactobacillus Casei, Bifidobacterium Bifidum, And Lactobacillus Plantarum Adverse Event Insights

12 reports name Enterococcus Faecium, Streptococcus Thermophilus, Lactobacillus Acidophilus, Lactobacillus Bulgaricus, Lactobacillus Casei, Bifidobacterium Bifidum, And Lactobacillus Plantarum; 3 recorded a death outcome (25.0% of reported events, not a population-level mortality rate). Active ingredient: Enterococcus Faecium, Streptococcus Thermophilus, Lactobacillus Acidophilus, Lactobacillus Bulgaricus, Lactobacillus Casei, Bifidobacterium Bifidum, And Lactobacillus Plantarum. Administration route: Unknown.

By species: Dog (12 reports). By breed: Retriever - Labrador (4), Chihuahua (1), Unknown (1).

Leading clinical signs: Diarrhoea (9), Vomiting (7), Decreased appetite (3), Lethargy (see also Central nervous system depression in 'Neurological') (3). Outcome, 12 coded reports: Ongoing leads at 33.3%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.