Drug profile

The FDA adverse-event record for Enrofloxacin, Silver Sulfadiazine

24 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Enrofloxacin, Silver Sulfadiazine. See the species affected, top reactions, and outcomes below.

24
adverse-event reports
0.0%
death-coded share
Unknown
most-reported species
6
Applicator, Abnormal - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
24
Total Reports
0
Deaths Reported
0.0%
Death Rate

Active Ingredients

Enrofloxacin, Silver Sulfadiazine

Administration Routes

UnknownAuricular (Otic)

Species Affected

Unknown 15
Dog 6
Cat 3

Most Affected Breeds

Unknown 15
Domestic (unspecified) 3
Retriever - Labrador 2
Shepherd Dog - German 1
Poodle (unspecified) 1
Terrier - Yorkshire 1
Spaniel (unspecified) 1

Most Reported Reactions

Applicator, Abnormal 6
Vials, Leaking 3
Caps, Abnormal 3
Vomiting 2
Pinnal erythema 2
Vials, Abnormal 2
Product label issues 1
Containers, Abnormal 1
Systemic disorder NOS 1
Urination 1
Nystagmus 1
Application site erythema 1

Outcome Breakdown

Ongoing
2 (66.7%)
Outcome Unknown
1 (33.3%)

Enrofloxacin, Silver Sulfadiazine Adverse Event Insights

24 reports name Enrofloxacin, Silver Sulfadiazine; 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). Active ingredient: Enrofloxacin, Silver Sulfadiazine. Administration routes: Unknown, Auricular (Otic).

By species: Unknown (15 reports), Dog (6 reports), Cat (3 reports). By breed: Unknown (15), Domestic (unspecified) (3), Retriever - Labrador (2).

Leading clinical signs: Applicator, Abnormal (6), Vials, Leaking (3), Caps, Abnormal (3), Vomiting (2). Outcome, 3 coded reports: Ongoing leads at 66.7%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.