Drug profile

The FDA adverse-event record for Emodepside, Praziquantel

305 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Emodepside, Praziquantel. See the species affected, top reactions, and outcomes below.

305
adverse-event reports
6.6%
death-coded share
Cat
most-reported species
86
Application site alopecia - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
305
Total Reports
20
Deaths Reported
6.6%
Death Rate

Active Ingredients

Emodepside, Praziquantel

Administration Routes

TopicalOralUnknownOther

Species Affected

Cat 299
Human 3
Unknown 2
Dog 1

Most Affected Breeds

Domestic (unspecified) 263
Cat (unknown) 18
Unknown 5
Himalayan 4
Siamese 4
Maine Coon 2
Manx 1
Ragdoll 1
Russian 1
Egyptian Mau 1

Most Reported Reactions

Application site alopecia 86
Hypersalivation 81
Depression 50
Vomiting 49
Anorexia 45
Ataxia 28
Application site pruritus 25
Trembling 21
Application site inflammation 21
Diarrhoea 18
Application site erythema 17
Death 15

Outcome Breakdown

Died
20 (87.0%)
Recovered/Normal
1 (4.3%)
Outcome Unknown
1 (4.3%)
Ongoing
1 (4.3%)

Emodepside, Praziquantel Adverse Event Insights

305 reports name Emodepside, Praziquantel; 20 recorded a death outcome (6.6% of reported events, not a population-level mortality rate). Active ingredient: Emodepside, Praziquantel. Administration routes: Topical, Oral, Unknown, Other.

By species: Cat (299 reports), Human (3 reports), Unknown (2 reports). By breed: Domestic (unspecified) (263), Cat (unknown) (18), Unknown (5).

Leading clinical signs: Application site alopecia (86), Hypersalivation (81), Depression (50), Vomiting (49). Outcome, 23 coded reports: Died leads at 87.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.