Drug profile

The FDA adverse-event record for Ear Flush

75 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Ear Flush. Species, reactions, and outcomes follow.

#905 of 2,679
by report volume (all drugs)
75
adverse-event reports
5.3%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Ear Flush ranks #905 of 2679 by total reports (75) and #773 of 1130 by death-coded share (5.3%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#905
This drug, reports of 2679
#773
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Ear Flush has 75 reports now versus 75 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Ear Flush changes

Signature read: Ear Flush's 5.3% death-coded share is among the lowest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
75
Total Reports
4
Deaths Reported
5.3%
Death-coded share of reports

Active Ingredients

Ear Flush

Administration Routes

Auricular (Otic)UnknownTopicalOral

Species Affected

Dog 60
Cat 14
Rabbit 1

Most Affected Breeds

Retriever - Labrador 9
Domestic Shorthair 8
Crossbred Canine/dog 5
Shih Tzu 4
Chihuahua 3
Shar Pei 2
Pug 2
Maltese 2
Bichon Frise 2
Coton de Tuléar 2

Most Reported Reactions

Ataxia 9
Head tilt - ear disorder 8
Lack of efficacy - NOS 8
Anorexia 7
Corneal ulcer 7
Dry nose 7
Ocular discharge 7
Vestibular disorder NOS 6
Lethargy (see also Central nervous system depression in 'Neurological') 6
Decreased appetite 6
Nystagmus 6
Deafness 6

Outcome Breakdown

Outcome Unknown
37 (49.3%)
Recovered/Normal
16 (21.3%)
Ongoing
14 (18.7%)
Recovered with Sequela
4 (5.3%)
Died
3 (4.0%)
Euthanized
1 (1.3%)

Ear Flush: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Nationwide drugs with similar profiles

Two openFDA-derived peer sets for Ear Flush, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Ear Flush (#905 of 2,679 by report volume); death-coded 5.3%. PlainBreed drug row · death-coded share stamp 5.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →