Drug profile

The FDA adverse-event record for Douxo Chlorhexidine Micro-Emulsion Spray

39 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Douxo Chlorhexidine Micro-Emulsion Spray. Species, reactions, and outcomes follow.

#1266 of 2,679
by report volume (all drugs)
39
adverse-event reports
0.0%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Douxo Chlorhexidine Micro-Emulsion Spray ranks #1263 of 2679 by total reports (39). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1263
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Douxo Chlorhexidine Micro-Emulsion Spray has 39 reports now versus 37 in that prior snapshot: 2 more (5.4%).

Report change
+2
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Douxo Chlorhexidine Micro-Emulsion Spray changes

Signature read: Douxo Chlorhexidine Micro-Emulsion Spray's 0.0% death-coded share is among the lowest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
39
Total Reports
0
Deaths Reported
0.0%
Death-coded share of reports

Active Ingredients

Douxo Chlorhexidine Micro-Emulsion Spray

Administration Routes

TopicalUnknownOphthalmic

Species Affected

Dog 38
Human 1

Most Affected Breeds

Crossbred Canine/dog 8
Retriever - Golden 4
Dog (unknown) 3
Shepherd Dog - German 2
Pekingese 2
Terrier (unspecified) 2
Retriever - Labrador 2
Terrier - Yorkshire 1
Havanese 1
Pointing Dog - Hungarian Short-haired (Vizsla) 1

Most Reported Reactions

Application site erythema 18
Application site reddening 5
Application site pruritus 4
Application site inflammation 3
Application site irritation 3
Application site swelling 3
Lack of efficacy - NOS 3
Diarrhoea 2
Emesis 2
Peeling skin 2
Loose stool 2
Application site pain 2

Outcome Breakdown

Recovered/Normal
19 (48.7%)
Ongoing
14 (35.9%)
Outcome Unknown
6 (15.4%)

Douxo Chlorhexidine Micro-Emulsion Spray: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Douxo Chlorhexidine Micro-Emulsion Spray (#1266 of 2,679 by report volume); death-coded 0.0%. PlainBreed drug row · death-coded share stamp 0.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →