Drug profile

The FDA adverse-event record for Domperidone

22 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Domperidone. See the species affected, top reactions, and outcomes below.

22
adverse-event reports
0.0%
death-coded share
Horse
most-reported species
4
Neurological signs NOS - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
22
Total Reports
0
Deaths Reported
0.0%
Death Rate

Active Ingredients

Domperidone

Administration Routes

OralUnknown

Species Affected

Horse 16
Dog 3
Unknown 3

Most Affected Breeds

Quarter Horse 5
Horse (unknown) 3
Thoroughbred 3
Unknown 3
Arab 2
Miniature 1
Anglo Arab 1
Doberman Pinscher 1
Mountain Dog - Bernese 1
Boxer (German Boxer) 1

Most Reported Reactions

Neurological signs NOS 4
Accidental exposure 3
Ataxia 3
Depression 2
Head down 2
Head bobbing 2
Head tremor 2
Abnormal serum protein NOS 2
Uncoded sign 1
Acute mastitis 1
Lack of efficacy - NOS 1
Increased sweating 1

Outcome Breakdown

Recovered/Normal
11 (57.9%)
Outcome Unknown
6 (31.6%)
Ongoing
2 (10.5%)

Domperidone Adverse Event Insights

22 reports name Domperidone; 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). Active ingredient: Domperidone. Administration routes: Oral, Unknown.

By species: Horse (16 reports), Dog (3 reports), Unknown (3 reports). By breed: Quarter Horse (5), Horse (unknown) (3), Thoroughbred (3).

Leading clinical signs: Neurological signs NOS (4), Accidental exposure (3), Ataxia (3), Depression (2). Outcome, 19 coded reports: Recovered/Normal leads at 57.9%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.