Drug profile

The FDA adverse-event record for Distemper

57 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Distemper. See the species affected, top reactions, and outcomes below.

57
adverse-event reports
7.0%
death-coded share
Dog
most-reported species
11
Lethargy (see also Central nervous system depression in 'Neurological') - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
57
Total Reports
4
Deaths Reported
7.0%
Death Rate

Active Ingredients

Distemper

Administration Routes

UnknownSubcutaneous

Species Affected

Dog 32
Cat 25

Most Affected Breeds

Domestic Shorthair 15
Domestic Longhair 5
Domestic Mediumhair 4
Chihuahua 3
Crossbred Canine/dog 3
Deutsche Dogge, Great Dane 3
Retriever - Golden 2
Shih Tzu 2
Shepherd Dog - Australian 2
Mixed (Dog) 1

Most Reported Reactions

Lethargy (see also Central nervous system depression in 'Neurological') 11
Vomiting 11
Application site alopecia 8
Emesis (multiple) 8
Diarrhoea 7
Hypersalivation 7
Emesis 6
Ataxia 6
Application site lesion 4
Pyrexia 4
Lack of efficacy (endoparasite) - hookworm 4
Adipsia 3

Outcome Breakdown

Recovered/Normal
33 (57.9%)
Outcome Unknown
16 (28.1%)
Ongoing
4 (7.0%)
Euthanized
3 (5.3%)
Died
1 (1.8%)

Distemper Adverse Event Insights

57 reports name Distemper; 4 recorded a death outcome (7.0% of reported events, not a population-level mortality rate). Active ingredient: Distemper. Administration routes: Unknown, Subcutaneous.

By species: Dog (32 reports), Cat (25 reports). By breed: Domestic Shorthair (15), Domestic Longhair (5), Domestic Mediumhair (4).

Leading clinical signs: Lethargy (see also Central nervous system depression in 'Neurological') (11), Vomiting (11), Application site alopecia (8), Emesis (multiple) (8). Outcome, 57 coded reports: Recovered/Normal leads at 57.9%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.