Diphenhydramine Injection

25 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

Total Reports

Deaths Reported

400.0%

Death Rate

Active Ingredients

Diphenhydramine Injection

Administration Routes

UnknownSubcutaneousIntramuscular

Species Affected

Dog 20

Cat 5

Most Affected Breeds

Domestic Shorthair 4

Coton de Tuléar 3

Bulldog - French 3

Crossbred Canine/dog 2

Dachshund (unspecified) 2

Terrier - Boston 2

Terrier (unspecified) 2

Shih Tzu 1

Terrier - Bull - Staffordshire 1

Russian 1

Most Reported Reactions

Vomiting 9

Lethargy (see also Central nervous system depression in 'Neurological') 4

Blepharospasm 4

Corneal ulcer 4

Keratoconjunctivitis sicca 4

Schirmer tear test 4

Cranial nerve disorder 4

Dry nose 4

Keratitis 4

Hyperaemia 4

Anaphylaxis 4

Lethargy (see also Central nervous system depression in Neurological) 4

Outcome Breakdown

Recovered/Normal

10 (40.0%)

Outcome Unknown

7 (28.0%)

Ongoing

7 (28.0%)

Euthanized

1 (4.0%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.