Dinotefuran + Pyriproxyfen
242 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
242
Total Reports
8
Deaths Reported
330.0%
Death Rate
Active Ingredients
DinotefuranDinotefuran + PyriproxyfenPyriproxyfen
Administration Routes
TopicalUnknownOral
Species Affected
Dog 221
Cat 20
Unknown 1
Most Affected Breeds
Retriever - Labrador 28
Domestic Shorthair 13
Pit Bull 11
Retriever - Golden 11
Boxer (German Boxer) 10
Collie - Border 9
Chihuahua 8
Terrier (unspecified) 8
Crossbred Canine/dog 8
Terrier - Yorkshire 7
Most Reported Reactions
Emesis 59
Vomiting 46
Lethargy (see also Central nervous system depression in 'Neurological') 41
Diarrhoea 18
Lack of efficacy (ectoparasite) - flea 14
Emesis (multiple) 13
Lack of efficacy - NOS 12
Other abnormal test result NOS 10
Behavioural disorder NOS 10
Weight loss 9
Seizure NOS 8
INEFFECTIVE, HOOKS 8
Outcome Breakdown
Recovered/Normal
135 (56.0%)
Outcome Unknown
75 (31.1%)
Ongoing
12 (5.0%)
Recovered with Sequela
11 (4.6%)
Euthanized
6 (2.5%)
Died
2 (0.8%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.