Dinotefuran + Permethrin + Pyriproxyfen

14 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

Total Reports

Deaths Reported

0.0%

Death Rate

Active Ingredients

DinotefuranPermethrinPyriproxyfen

Administration Routes

TopicalUnknown

Species Affected

Dog 14

Most Affected Breeds

Crossbred Canine/dog 2

Boxer (German Boxer) 2

Shepherd Dog - Australian 2

Siberian Husky 1

Pointing Dog - German Short-haired 1

Sheepdog - Shetland 1

Chihuahua 1

Bulldog 1

Dog (unknown) 1

Retriever - Labrador 1

Most Reported Reactions

Pruritus 3

Application site irritation 3

Application site erythema 2

Application site reddening 2

Emesis 2

Lack of efficacy (endoparasite) - heartworm 2

Application site pustule 1

Anxiety 1

Restlessness 1

Sleep disturbance NOS 1

Erythema (for urticaria see Immune SOC) 1

Application site twitching 1

Outcome Breakdown

Recovered/Normal

8 (57.1%)

Ongoing

3 (21.4%)

Outcome Unknown

2 (14.3%)

Recovered with Sequela

1 (7.1%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.