Drug profile

The FDA adverse-event record for Dinoprost Tromethamine

705 FDA reports name Dinoprost Tromethamine, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#235 of 2,679
by report volume (all drugs)
705
adverse-event reports
25.0%
death-coded share
Cattle
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Dinoprost Tromethamine ranks #235 of 2679 by total reports (705) and #175 of 1130 by death-coded share (25.0%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#235
This drug, reports of 2679
#175
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Dinoprost Tromethamine has 705 reports now versus 702 in that prior snapshot: 3 more (0.4%).

Report change
+3
Death-coded reports
+2
Death-coded share
+0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Dinoprost Tromethamine changes

Signature read: death-coded report count at 176 is the most distinctive stamp on Dinoprost Tromethamine's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
705
Total Reports
176
Deaths Reported
25.0%
Death-coded share of reports

Active Ingredients

Dinoprost Tromethamine

Administration Routes

IntramuscularUnknownSubcutaneousTopicalIntravenousOralOtherParenteralRespiratory (Inhalation)Ophthalmic

Species Affected

Cattle 518
Unknown 65
Human 64
Horse 27
Pig 14
Goat 8
Dog 7
Cat 2

Most Affected Breeds

Mixed (Cattle) 134
Unknown 129
Cattle (other) 114
Holstein-Friesian also known as Holstein 110
Aberdeen Angus 54
Cattle (unknown) 31
Jersey 15
Cattle (unspecified) 14
Hereford cattle 13
Quarter Horse 10

Most Reported Reactions

Lack of efficacy - NOS 236
INEFFECTIVE, ESTRUS SYNCHRONIZ 133
Death 130
Injection site swelling 89
Myositis 41
INEFFECTIVE, ABORTION 32
Accidental exposure 27
Death by euthanasia 24
Injection site pain 19
Recumbency 18
Injection site infection 16
Injection site inflammation 16

Outcome Breakdown

Outcome Unknown
369 (53.4%)
Died
161 (23.3%)
Recovered/Normal
72 (10.4%)
Ongoing
54 (7.8%)
Euthanized
30 (4.3%)
Recovered with Sequela
5 (0.7%)

Dinoprost Tromethamine: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Dinoprost Tromethamine, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

  • Compare Dinoprost Tromethamine's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Dinoprost Tromethamine (#235 of 2,679 by report volume); death-coded 25.0%. PlainBreed drug row · death-coded report count stamp 176 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →