Dinoprost Tromethamine

697 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

697

Total Reports

171

Deaths Reported

2450.0%

Death Rate

Active Ingredients

Dinoprost Tromethamine

Administration Routes

IntramuscularUnknownSubcutaneousTopicalIntravenousOralOtherRespiratory (Inhalation)ParenteralOphthalmic

Species Affected

Cattle 511

Unknown 65

Human 63

Horse 27

Pig 14

Goat 8

Dog 7

Cat 2

Most Affected Breeds

Mixed (Cattle) 133

Unknown 128

Holstein-Friesian also known as Holstein 110

Cattle (other) 110

Aberdeen Angus 54

Cattle (unknown) 30

Jersey 14

Cattle (unspecified) 14

Hereford cattle 13

Quarter Horse 10

Most Reported Reactions

Lack of efficacy - NOS 234

INEFFECTIVE, ESTRUS SYNCHRONIZ 133

Death 126

Injection site swelling 87

Myositis 39

INEFFECTIVE, ABORTION 32

Accidental exposure 26

Death by euthanasia 23

Recumbency 18

Injection site pain 18

Injection site infection 16

Injection site inflammation 16

Outcome Breakdown

Outcome Unknown

365 (53.8%)

Died

157 (23.2%)

Recovered/Normal

70 (10.3%)

Ongoing

52 (7.7%)

Euthanized

29 (4.3%)

Recovered with Sequela

5 (0.7%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.