Drug profile

The FDA adverse-event record for Dimethyl Sulfoxide; Fluocinolone Acetonide

56 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Dimethyl Sulfoxide; Fluocinolone Acetonide. Species, reactions, and outcomes follow.

#1044 of 2,679
by report volume (all drugs)
56
adverse-event reports
1.8%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Dimethyl Sulfoxide; Fluocinolone Acetonide ranks #1044 of 2679 by total reports (56) and #1005 of 1130 by death-coded share (1.8%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1044
This drug, reports of 2679
#1005
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Dimethyl Sulfoxide; Fluocinolone Acetonide has 56 reports now versus 56 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Dimethyl Sulfoxide; Fluocinolone Acetonide changes

Signature read: Dimethyl Sulfoxide; Fluocinolone Acetonide's 1.8% death-coded share is among the lowest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
56
Total Reports
1
Deaths Reported
1.8%
Death-coded share of reports

Active Ingredients

Dimethyl Sulfoxide; Fluocinolone Acetonide

Administration Routes

UnknownTopicalAuricular (Otic)OphthalmicNasal

Species Affected

Dog 22
Unknown 17
Human 11
Cat 6

Most Affected Breeds

Unknown 28
Pug 3
Havanese 3
Retriever - Labrador 2
Domestic Shorthair 2
Dog (unknown) 2
Mixed (Dog) 2
Cat (unknown) 1
Griffon - Brussels 1
Doberman Pinscher 1

Most Reported Reactions

Caps, Abnormal 7
Uncoded sign 7
Vomiting 6
Lethargy (see also Central nervous system depression in 'Neurological') 6
Accidental exposure 6
No sign 6
Vials, Leaking 5
Behavioural disorder NOS 5
Lack of efficacy - NOS 4
Containers, Leaking 4
Anaemia NOS 3
Underfilling, Bottles 3

Outcome Breakdown

Ongoing
17 (43.6%)
Outcome Unknown
12 (30.8%)
Recovered/Normal
9 (23.1%)
Died
1 (2.6%)

Dimethyl Sulfoxide; Fluocinolone Acetonide: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Nationwide drugs with similar profiles

Two openFDA-derived peer sets for Dimethyl Sulfoxide; Fluocinolone Acetonide, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar death-coded share

Nearest other drugs by death-coded share (1.8% here), distinct from the volume row.

What to do with this drug

  • Compare Dimethyl Sulfoxide; Fluocinolone Acetonide's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Dimethyl Sulfoxide; Fluocinolone Acetonide (#1044 of 2,679 by report volume); death-coded 1.8%. PlainBreed drug row · death-coded share stamp 1.8% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →