Diethylstilbestrol (Des)

86 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
86
Total Reports
10
Deaths Reported
1160.0%
Death Rate

Active Ingredients

Diethylstilbestrol (Des)

Administration Routes

OralUnknown

Species Affected

Dog 86

Most Affected Breeds

Retriever - Labrador 13
Shepherd Dog - German 5
Doberman Pinscher 4
Crossbred Canine/dog 4
Boxer (German Boxer) 4
Schnauzer - Miniature 4
Shepherd Dog - Australian 3
Beagle 2
Retriever - Golden 2
Pit Bull 2

Most Reported Reactions

Vomiting 23
Emesis 19
Lethargy (see also Central nervous system depression in 'Neurological') 13
Anorexia 8
Death by euthanasia 7
Other abnormal test result NOS 7
Elevated alanine aminotransferase (ALT) 7
Lack of efficacy - NOS 7
Elevated serum alkaline phosphatase (SAP) 7
Decreased appetite 7
Seizure NOS 6
Urinary incontinence 6

Outcome Breakdown

Recovered/Normal
40 (46.5%)
Outcome Unknown
19 (22.1%)
Ongoing
14 (16.3%)
Euthanized
7 (8.1%)
Recovered with Sequela
3 (3.5%)
Died
3 (3.5%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.