Drug profile

The FDA adverse-event record for Dietary Supplement (Unknown)

120 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Dietary Supplement (Unknown). See the species affected, top reactions, and outcomes below.

120
adverse-event reports
4.2%
death-coded share
Dog
most-reported species
23
Emesis - top reaction
Verify with FDA CVM →
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
120
Total Reports
5
Deaths Reported
4.2%
Death Rate

Active Ingredients

Dietary Supplement (Unknown)

Administration Routes

OralUnknownOphthalmic

Species Affected

Dog 92
Cat 25
Human 2
Horse 1

Most Affected Breeds

Domestic Shorthair 14
Retriever - Labrador 8
Shepherd Dog - Australian 7
Collie - Border 6
Crossbred Canine/dog 5
Terrier - West Highland White 4
Retriever - Golden 4
Cat (unknown) 4
Chihuahua 3
Siberian Husky 3

Most Reported Reactions

Emesis 23
Vomiting 18
Lethargy (see also Central nervous system depression in 'Neurological') 17
Lack of efficacy - NOS 16
Lack of efficacy (ectoparasite) - flea 15
Diarrhoea 15
Not eating 10
Weight loss 9
Scratching 6
Behavioural disorder NOS 6
Other abnormal test result NOS 6
Weight gain 5

Outcome Breakdown

Recovered/Normal
44 (36.7%)
Outcome Unknown
37 (30.8%)
Ongoing
24 (20.0%)
Recovered with Sequela
10 (8.3%)
Euthanized
3 (2.5%)
Died
2 (1.7%)

Dietary Supplement (Unknown) Adverse Event Insights

120 reports name Dietary Supplement (Unknown); 5 recorded a death outcome (4.2% of reported events, not a population-level mortality rate). Active ingredient: Dietary Supplement (Unknown). Administration routes: Oral, Unknown, Ophthalmic.

By species: Dog (92 reports), Cat (25 reports), Human (2 reports). By breed: Domestic Shorthair (14), Retriever - Labrador (8), Shepherd Dog - Australian (7).

Leading clinical signs: Emesis (23), Vomiting (18), Lethargy (see also Central nervous system depression in 'Neurological') (17), Lack of efficacy - NOS (16). Outcome, 120 coded reports: Recovered/Normal leads at 36.7%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.