Drug profile

The FDA adverse-event record for Dextrose

258 FDA reports name Dextrose, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#466 of 2,679
by report volume (all drugs)
258
adverse-event reports
63.2%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Dextrose ranks #465 of 2679 by total reports (258) and #39 of 1130 by death-coded share (63.2%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#465
This drug, reports of 2679
#39
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Dextrose has 258 reports now versus 249 in that prior snapshot: 9 more (3.6%).

Report change
+9
Death-coded reports
+5
Death-coded share
−0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Dextrose changes

Signature read: Dextrose's 63.2% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
258
Total Reports
163
Deaths Reported
63.2%
Death-coded share of reports

Active Ingredients

Dextrose

Administration Routes

UnknownIntravenousParenteralOralSubcutaneousIntraperitonealOtherTransdermalIntradermal

Species Affected

Dog 179
Cat 78
Rabbit 1

Most Affected Breeds

Domestic Shorthair 55
Retriever - Labrador 23
Chihuahua 11
Retriever - Golden 10
Terrier - Yorkshire 9
Shih Tzu 7
Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne)) 6
Domestic Longhair 5
Terrier - Bull - American Pit 5
Bulldog - French 5

Most Reported Reactions

Hypoglycaemia 129
Death by euthanasia 87
Death 78
Vomiting 72
Other abnormal test result NOS 64
Elevated total bilirubin 57
Lethargy (see also Central nervous system depression in 'Neurological') 52
Elevated alanine aminotransferase (ALT) 50
Not eating 49
Leucocytosis NOS 45
Anorexia 44
Dehydration 44

Outcome Breakdown

Euthanized
86 (32.6%)
Died
79 (29.9%)
Ongoing
50 (18.9%)
Recovered/Normal
28 (10.6%)
Outcome Unknown
21 (8.0%)

Dextrose: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Dextrose, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar report volume

Nearest other drugs by FDA report count (258 here).

Similar death-coded share

Nearest other drugs by death-coded share (63.2% here), distinct from the volume row.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Dextrose (#466 of 2,679 by report volume); death-coded 63.2%. PlainBreed drug row · death-coded share stamp 63.2% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →