Drug profile

The FDA adverse-event record for Dexmedetomidine,Ketamine

25 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Dexmedetomidine,Ketamine. See the species affected, top reactions, and outcomes below.

25
adverse-event reports
12.0%
death-coded share
Cat
most-reported species
5
Application site alopecia - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
25
Total Reports
3
Deaths Reported
12.0%
Death Rate

Active Ingredients

Dexmedetomidine,Ketamine

Administration Routes

UnknownIntramuscularParenteralOther

Species Affected

Cat 25

Most Affected Breeds

Domestic Shorthair 14
Domestic Mediumhair 4
Cat (unknown) 3
Maine Coon 2
Siamese 1
Domestic (unspecified) 1

Most Reported Reactions

Application site alopecia 5
Not eating 4
Elevated temperature 4
Other abnormal test result NOS 4
Falling 4
Hypersalivation 4
Death by euthanasia 3
Behavioural disorder NOS 3
Decreased body temperature 3
Panting 3
Distress 3
Icterus 2

Outcome Breakdown

Ongoing
13 (52.0%)
Outcome Unknown
5 (20.0%)
Recovered/Normal
4 (16.0%)
Euthanized
3 (12.0%)

Dexmedetomidine,Ketamine Adverse Event Insights

25 reports name Dexmedetomidine,Ketamine; 3 recorded a death outcome (12.0% of reported events, not a population-level mortality rate). Active ingredient: Dexmedetomidine,Ketamine. Administration routes: Unknown, Intramuscular, Parenteral, Other.

By species: Cat (25 reports). By breed: Domestic Shorthair (14), Domestic Mediumhair (4), Cat (unknown) (3).

Leading clinical signs: Application site alopecia (5), Not eating (4), Elevated temperature (4), Other abnormal test result NOS (4). Outcome, 25 coded reports: Ongoing leads at 52.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.