Dexmedetomidine Hydrochloride

4,754 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

4,754

Total Reports

653

Deaths Reported

1370.0%

Death Rate

Active Ingredients

Dexmedetomidine Hydrochloride

Administration Routes

IntramuscularUnknownIntravenousBuccalSublingualOralSubcutaneousOtherTopicalParenteral

Species Affected

Dog 3,291

Cat 1,172

Unknown 175

Human 44

Rabbit 14

Rat 6

Other 5

Horse 4

Other Mammals 4

Guinea Pig 4

Most Affected Breeds

Dog (unknown) 585

Domestic Shorthair 490

Retriever - Labrador 320

Unknown 277

Domestic (unspecified) 157

Cat (unknown) 155

Cat (other) 129

Terrier - Bull - American Pit 119

Shepherd Dog - German 118

Crossbred Canine/dog 118

Most Reported Reactions

INEFFECTIVE, SEDATION 649

Lack of efficacy - NOS 562

Bradycardia 501

Death 466

Vomiting 351

Cardiac arrest 304

Lethargy (see also Central nervous system depression in 'Neurological') 246

Sedation prolonged 217

Sedation 201

Hypersalivation 182

Underdose 180

Anorexia 176

Outcome Breakdown

Recovered/Normal

1,656 (41.5%)

Ongoing

1,136 (28.4%)

Outcome Unknown

545 (13.6%)

Died

537 (13.4%)

Euthanized

118 (3.0%)

Recovered with Sequela

3 (0.1%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.