Dexamethasone + Neomycin Sulfate + Thiabendazole

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791 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
791
Total Reports
42
Deaths Reported
530.0%
Death Rate

Active Ingredients

DexamethasoneNeomycin SulfateThiabendazole

Administration Routes

Auricular (Otic)UnknownOphthalmicTopicalOtherIntraocularOralTransdermalIntrauterineVaginal

Species Affected

Cat 363
Dog 194
Unknown 173
Human 56
Ferret 3
Mouse 1
Guinea Pig 1

Most Affected Breeds

Unknown 231
Domestic Shorthair 209
Cat (unknown) 40
Domestic Longhair 27
Domestic Mediumhair 19
Siamese 17
Terrier - Yorkshire 16
Retriever - Labrador 14
Retriever - Golden 14
Dog (unknown) 14

Most Reported Reactions

Lethargy (see also Central nervous system depression in 'Neurological') 72
Vomiting 71
Vials, Damaged 56
Lethargy (see also Central nervous system depression in Neurological) 55
Not eating 48
Elevated alanine aminotransferase (ALT) 43
Lack of efficacy - NOS 43
Anorexia 39
Closure, Abnormal 38
Underdose 36
Ataxia 35
Containers, Leaking 33

Outcome Breakdown

Outcome Unknown
393 (63.6%)
Recovered/Normal
109 (17.6%)
Ongoing
72 (11.7%)
Euthanized
30 (4.9%)
Died
12 (1.9%)
Recovered with Sequela
2 (0.3%)

Data Summary

Metric Value
Total adverse event reports 791
Reports involving death 42
Case-fatality rate (reported events) 530.0%
Distinct species in reports 7
Distinct breeds in reports 20
Distinct reactions reported 20
Active ingredients on file 3

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Dexamethasone + Neomycin Sulfate + Thiabendazole Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 791 adverse event reports referencing Dexamethasone + Neomycin Sulfate + Thiabendazole, including 42 reports in which the animal died — a 530.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredients on file: Dexamethasone, Neomycin Sulfate, Thiabendazole. Reported administration routes include Auricular (Otic), Unknown, Ophthalmic, Topical. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Dexamethasone + Neomycin Sulfate + Thiabendazole reports are Cat (363 reports), Dog (194 reports), Unknown (173 reports), with Cat accounting for the largest share. Within those species, Unknown (231), Domestic Shorthair (209), Cat (unknown) (40) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Dexamethasone + Neomycin Sulfate + Thiabendazole are Lethargy (see also Central nervous system depression in 'Neurological') (72), Vomiting (71), Vials, Damaged (56), Lethargy (see also Central nervous system depression in Neurological) (55). Of the 618 reports with a coded outcome, Outcome Unknown is the leading category at 63.6%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Dexamethasone + Neomycin Sulfate + Thiabendazole.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial