Drug profile

The FDA adverse-event record for Dexamethasone + Neomycin Sulfate + Thiabendazole

791 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Dexamethasone + Neomycin Sulfate + Thiabendazole. See the species affected, top reactions, and outcomes below.

791
adverse-event reports
5.3%
death-coded share
Cat
most-reported species
72
Lethargy (see also Central nervous system depression in 'Neurological') - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
791
Total Reports
42
Deaths Reported
5.3%
Death Rate

Active Ingredients

DexamethasoneNeomycin SulfateThiabendazole

Administration Routes

Auricular (Otic)UnknownOphthalmicTopicalOtherIntraocularOralTransdermalIntrauterineVaginal

Species Affected

Cat 363
Dog 194
Unknown 173
Human 56
Ferret 3
Mouse 1
Guinea Pig 1

Most Affected Breeds

Unknown 231
Domestic Shorthair 209
Cat (unknown) 40
Domestic Longhair 27
Domestic Mediumhair 19
Siamese 17
Terrier - Yorkshire 16
Retriever - Labrador 14
Retriever - Golden 14
Dog (unknown) 14

Most Reported Reactions

Lethargy (see also Central nervous system depression in 'Neurological') 72
Vomiting 71
Vials, Damaged 56
Lethargy (see also Central nervous system depression in Neurological) 55
Not eating 48
Elevated alanine aminotransferase (ALT) 43
Lack of efficacy - NOS 43
Anorexia 39
Closure, Abnormal 38
Underdose 36
Ataxia 35
Containers, Leaking 33

Outcome Breakdown

Outcome Unknown
393 (63.6%)
Recovered/Normal
109 (17.6%)
Ongoing
72 (11.7%)
Euthanized
30 (4.9%)
Died
12 (1.9%)
Recovered with Sequela
2 (0.3%)

Dexamethasone + Neomycin Sulfate + Thiabendazole Adverse Event Insights

791 reports name Dexamethasone + Neomycin Sulfate + Thiabendazole; 42 recorded a death outcome (5.3% of reported events, not a population-level mortality rate). Active ingredients: Dexamethasone, Neomycin Sulfate, Thiabendazole. Administration routes: Auricular (Otic), Unknown, Ophthalmic, Topical.

By species: Cat (363 reports), Dog (194 reports), Unknown (173 reports). By breed: Unknown (231), Domestic Shorthair (209), Cat (unknown) (40).

Leading clinical signs: Lethargy (see also Central nervous system depression in 'Neurological') (72), Vomiting (71), Vials, Damaged (56), Lethargy (see also Central nervous system depression in Neurological) (55). Outcome, 618 coded reports: Outcome Unknown leads at 63.6%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.