Drug profile

The FDA adverse-event record for Dexamethasone + Neomycin Sulfate + Polymyxin B Sulfate

14 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Dexamethasone + Neomycin Sulfate + Polymyxin B Sulfate. See the species affected, top reactions, and outcomes below.

14
adverse-event reports
7.1%
death-coded share
Dog
most-reported species
3
Decreased appetite - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
14
Total Reports
1
Deaths Reported
7.1%
Death Rate

Active Ingredients

Dexamethasone + Neomycin Sulfate + Polymyxin B Sulfate

Administration Routes

UnknownOphthalmicTopicalIntraocular

Species Affected

Dog 14

Most Affected Breeds

Maltese 4
Crossbred Canine/dog 3
Poodle - Miniature 1
Shiba Inu 1
Retriever - Labrador 1
Terrier - West Highland White 1
Shih Tzu 1
Bulldog - English 1
Boxer (German Boxer) 1

Most Reported Reactions

Decreased appetite 3
Crust 3
Erythema (for urticaria see Immune SOC) 3
Lack of efficacy (endoparasite) - hookworm 3
Deafness 2
Elevated serum alkaline phosphatase (SAP) 2
Elevated alanine aminotransferase (ALT) 2
Elevated gamma-glutamyl transferase (GGT) 2
Local swelling (not application site) 2
Hyperpigmentation 2
Pinnae disorder 2
Loose stool 2

Outcome Breakdown

Outcome Unknown
8 (57.1%)
Ongoing
3 (21.4%)
Recovered with Sequela
1 (7.1%)
Recovered/Normal
1 (7.1%)
Died
1 (7.1%)

Dexamethasone + Neomycin Sulfate + Polymyxin B Sulfate Adverse Event Insights

14 reports name Dexamethasone + Neomycin Sulfate + Polymyxin B Sulfate; 1 recorded a death outcome (7.1% of reported events, not a population-level mortality rate). Active ingredient: Dexamethasone + Neomycin Sulfate + Polymyxin B Sulfate. Administration routes: Unknown, Ophthalmic, Topical, Intraocular.

By species: Dog (14 reports). By breed: Maltese (4), Crossbred Canine/dog (3), Poodle - Miniature (1).

Leading clinical signs: Decreased appetite (3), Crust (3), Erythema (for urticaria see Immune SOC) (3), Lack of efficacy (endoparasite) - hookworm (3). Outcome, 14 coded reports: Outcome Unknown leads at 57.1%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.